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From protein–protein interaction to therapy response: Molecular imaging of heat shock proteins
European Journal of Radiology, 05/22/09
Niu G et al. - The authors summarize exciting applications of newly emerged molecular imaging techniques as they relate to HSP, including protein–protein interactions of HSP90 complexes, therapeutic response of tumors to HSP90 inhibitors, and HSP70 promoters-controlled gene therapy. In the HSPs context, molecular imaging is expected to play a vital role in promoting drug development and advancing individualized medicine.
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