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The response of gamma-H2AX in human lymphocytes and lymphocytes subsets measured in whole blood cultures
International Journal of Radiation Biology, 04/29/09
Andrievski A et al. - Differences in the expression level of ?-H2AX between lymphocyte subsets were minimal. The usefulness of this assay for radiation biodosimetry is hampered by its relatively quick lifetime kinetics and large inter-individual variation. Therefore, it could only be useful if samples were obtained within 24 h of exposure. Even in this situation, the assay could only be used as an indicator of exposure and not a dosimeter.
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