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See Latest ArticlesEarly clinical signs and imaging findings in Gerstmann–Sträussler–Scheinker syndrome (Pro102Leu)
Neurology, 06/15/06
Conclusions: Key features for early diagnosis of Gerstmann–Sträussler–Scheinker syndrome caused by Pro102Leu mutation in PRNP (GSS102) are truncal ataxia, dysesthesia and hyporeflexia of the lower legs, and mild dysarthria. Normal cerebellar MRI and abnormal cerebral SPECT findings are characters of early GSS102
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