Submandibular TCD approach detects post-bulb ICA stenosis in children with sickle cell anemia
Gorman MJ et al. - Using the extended submandibular approach to evaluate these portions of the ICA, the authors identified stenotic lesions in 4 patients with Hb SS disease out of a population of 131 children with Hb SS. Three of the 4 patients had no history of overt stroke or stroke-like symptoms. Neuroimaging confirmed the stenotic lesions, and also revealed watershed infarction as well as discrete areas of silent infarction. All 4 children had neuropsychological impairment. The submandibular approach, when added to a standard transcranial Doppler examination, may increase the sensitivity of this technique to identify important potential sources of cerebral infarction. [more...]
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