Assessment of interstitial water content of articular cartilage with T1 relaxation Berberat JE et al. - The interstitial water content typically increases in the early degeneration of articular cartilage. Previously, T2 relaxation has been related to water content, yet it is known to be strongly affected by the collagen orientation. The spin-lattice relaxation rate is proposed to provide a biomarker for water content in articular cartilage. [more...]