Assessing the usefulness of a novel MRI-based breast density estimation algorithm in a cohort of women at high genetic risk of breast cancer: The UK MARIBS study
Breast Cancer Research, 11/17/2009
Thompson DJ et al. – The MRIBview estimates of volumetric breast density are highly correlated with mammographic dense area but are not equivalent measures; the MRI ... as a predictor of breast cancer risk that merits further investigation. Methods- Analyses based on MRI (n = 655) and mammography (n = 607) images obtained in course of UK multicentre magnetic resonance imaging breast screening (MARIBS) breast-screening study of asymptomatic ... years at high genetic risk of breast cancer
- MRI percent and absolute dense volumes estimated using novel algorithm (MRIBview) while mammographic percent and absolute dense area estimated using Cumulus thresholding algorithm and using 21-point visual assessment scale for 1 medio-lateral ... Assessed relationships of MRI and mammographic measures to one another, to standard anthropometric and hormonal factors, to BRCA1/2 genetic status, and breast cancer risk (60 cases) using linear and Poisson regression
Results- MRI percent dense volume well correlated with ... area, and to a lesser extent MRI percent dense volume lower in BRCA1 carriers but there was no association with BRCA2 carrier status
- Study was underpowered to detect expected associations between percent density and breast cancer, but women with absolute MRI dense volume in upper half of ... those in lower half
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Diagnosis of breast cancer at dynamic MRI in patients with breast augmentation by paraffin or silicone injection
Clinical Radiology, 11/13/2009
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Youk JH et al. – In patients with breasts injected with foreign material, MRI was used to successfully diagnose malignant breast lesions and could be the diagnostic method of ... of the morphological and kinetic features at MRI in conjunction with clinical findings is essential.
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Can breast MRI computer-aided detection improve radiologist accuracy for lesions detected at MRI screening and recommended for biopsy in a high-risk population
Clinical Radiology, 11/13/2009
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Arazi–Kleinman T et al. – The breast MRI CAD system used could not improve the radiologists' accuracy for distinguishing all ... malignant from benign lesions, due to the poor sensitivity for DCIS detection.
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Dynamic Contrast-Enhanced MRI of the Breast: Quantitative Method for Kinetic Curve Type Assessment
American Journal of Roentgenology, 10/08/2009
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Khouli RHE et al. – Quantitative assessment of the type of contrast enhancement kinetic curve on breast DCE–MRI resulted in significantly higher diagnostic performance for establishing or ... compared with assessment based on the standard qualitative method.
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Evaluating the Correlation between Film Mammography and MRI for Screening Women with Increased Breast Cancer Risk
Academic Radiology, 10/16/2009
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Lee JM et al. – Evidence from published trials of multimodality breast cancer screening identified no statistically significant correlation between film mammography and MRI. Using both tests for breast cancer screening ... improve the early detection of breast cancer in women at increased risk.
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Breast self-examination: defining a cohort still in need
The American Journal of Surgery, 10/08/2009
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Wilke LG et al. – BSE detects new breast cancers in high–risk women undergoing screening mammogram, CBE, and yearly breast MRI.
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Is there concordance of invasive breast cancer pathologic tumor size with magnetic resonance imaging
The American Journal of Surgery, 10/06/2009
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Grimsby GM et al. – Breast MRI is concordant with pathologic tumor size within .5 cm among 53% of patients. Most patients with tumors overestimated by MRI have significant findings in the surrounding breast tissue ... excision of which would be expected to benefit the patient.
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Role of diffusion MRI in characterizing benign and malignant breast lesions
Indian Journal of Radiology and Imaging, 10/29/2009
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Palle L et al. – DWI is a useful technique for characterizing breast tumors, especially for lesions that cannot be adequately characterized by ultrasonography and routine magnetic resonance imaging.
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Relationship of temporal resolution to diagnostic performance for dynamic contrast enhanced MRI of the breast
Journal of Magnetic Resonance Imaging, 10/30/2009
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Khouli RHE et al. – DCE MRI data with at least 45–s temporal resolution maximized the agreement between the kinetic parameters and correct classification of benign versus malignant diagnosis.
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Principal component analysis of breast DCE-MRI adjusted with a model-based method
Journal of Magnetic Resonance Imaging, 10/30/2009
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Eyal E et al. – PCA adjusted with a model–based method provided a fast and objective computer–aided diagnostic tool for breast DCE–MRI.
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