Conventional brain MRI in neuromyelitis optica
European Journal of Neurology, 04/18/2012
Cabrera–Gomez JA et al. – Brain lesions in neuromyelitis optica (NMO) are a consistent feature of the disease. International consensus MRI criteria are needed for NMO analogous to the existing criteria for multiple sclerosis (MS).Methods
- The authors searched for articles with descriptions of brain MRI findings in NMO in EBSCO, EMBASE, PubMed/Medline, Science Citation Index, and SCOPUS.
- Brain abnormalities are seen in majority of NMO patients as disease duration increases.
- A minority of NMO patients meet Barkhof criteria for space dissemination in multiple sclerosis (MS), and these criteria should not be used to exclude NMO diagnosis.
- Distinctive brain lesions of NMO are cataloged and described.