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A prospective randomised clinical pilot study to compare the effectiveness of Biobrane synthetic wound dressing, with or without autologous cell suspension, to the local standard treatment regimen in paediatric scald injuries
Burns,
Clinical Article
Wood F et al. – Investment of surgical resources in the acute stages within 4days of injury saved on nursing time, dressing, analgesic and scar management costs.
Methods- All paediatric patients with partial thickness scald injury were clinically assessed between July 1, 2009 and June 30, 2010.
- A burn of 2% TBSAB or more and deemed not to heal within 10days, were considered for the trial.
- These patients were randomised to one of three treatment arms: the local standard treatment (Intrasite, Acticoat and Duoderm dressings every 2–3days) with surgery at 10days, Biobrane only or Biobrane and autologous cell suspension using the ReCell kit.
- The primary outcome was surgery performed after 10days; secondary outcomes were rates of healing, pain experienced, and scar outcomes.
- 15% of scald presentations in the 12month period met the eligibility criteria.
- 13 patients were recruited into the pilot study; early intervention was associated with a decreased time to healing with fewer dressing changes, less pain and better scar outcomes.
