Quantitative short echo time 1H MRSI of the peripheral edematous region of human brain tumors in the differentiation between glioblastoma, metastasis, and meningioma
Journal of Magnetic Resonance Imaging, 06/29/2012
Wijnen JP et al. – Specific metabolite ratios in peritumoral edematous (PO) and surrounding apparently normal (SAN) regions can be used to discriminate glioblastoma from metastasis and meningioma. An analysis of these ratios averaged over entire regions of interest (ROIs) and those with most abnormal values indicates that infiltrative tumor growth in glioblastoma is inhomogeneous and extends into the SAN region.