This course is designed for neuroradiologists, general radiologists, and clinicians who have an interest in imaging of the brain, spine, and head and neck. The case material shown will include a wide spectrum of the diseases that affect these areas. The specific utilization of CT, MRI, MRS and perfusion-diffusion & permeability imaging in the investigation of these diseases will be discussed. In each section, the imaging protocols, anatomy, pathology, and the clinically relevant differential diagnoses will be reviewed. This course will improve the participant's ability to analyze CT and MR images, to offer a pertinent differential diagnosis, and to be familiar with the newest technologies applied to these regions.