Value of Fluorescence Cystoscopy in High Risk Non-muscle Invasive Bladder Cancer
Current Urology Reports, February 1, 2013
Mayr R et al. - While no specific and larger data on impact of PDD on cancer specific survival exist to date and the few long-term data suggest little impact, improved accuracy of diagnosis is suggested to be beneficial for clinical decision making and thus a value of PDD is postulated in the management of high-risk non-muscle invasive bladder cancer.
Photodynamic Diagnosis (PDD), an adjunct to white light cystoscopy, has been shown to improve detection and ...
Estrogen receptor β (ERβ) is a novel prognostic marker of recurrence survival in non-muscle-invasive bladder cancer potentially by inhibiting cadherin switch
World Journal of Urology, February 15, 2013
Han B et al. - In this study, the authors aimed to evaluate ERβ as a novel prognostic marker of recurrence free survival; and digest the underlying mechanism by elucidating the relationship between ERβ expression and cadherin switch. ERβ is a prognostic marker of recurrence free rate in non-muscle-invasive bladder cancer, potentially through suppressing cadherin switch, and may act as a potential target for bladder cancer therapy. Methods The authors ...
Impact of smoking status on bladder tumor recurrence after radical nephroureterectomy for upper tract urothelial carcinoma
The Journal of Urology, May 13, 2013
Hagiwara M et al. - Authors investigated the possible influence of smoking status on bladder tumor recurrence after radical nephroureterectomy. Positive smoking history and male gender were independent risk factors for bladder tumor recurrence after radical nephroureterectomy. A larger number of cigarettes smoked may increase the incidence of bladder tumor recurrence in patients with upper tract urothelial cancer. Methods Authors identified a study population of 245 consecutive ...
Finger taps and constipation are closely related to symptoms of overactive bladder in male patients with Parkinsons disease
International Journal of Urology, May 16, 2013
Tsujimura A et al. - This study aimed to assess which motor and non-motor symptoms are closely related to overactive bladder severity in male patients with Parkinson's disease. Although a study on a larger scale is required to further assess the association of Parkinson's disease symptoms with overactive bladder symptom score, information on finger taps and severity of constipation should be obtained when assessing urological patients with Parkinson's disease. Methods A ...
Egg consumption and risk of bladder cancer: a meta-analysis
Nutrition and Cancer, May 17, 2013
Li F et al. - These findings suggest no significant association between egg consumption and bladder cancer risk, except for a possible positive relationship with the intake of fried eggs based on the limited number of studies. Additional studies, especially large prospective cohort studies, are warranted to confirm these findings. Methods The findings of epidemiologic studies on the association between egg consumption and bladder cancer risk remain conflicting. Authors ...
Elevated 4-aminobiphenyl and 2, 6-dimethylaniline hemoglobin adducts and increased risk of bladder cancer among lifelong nonsmokers - The Shanghai Bladder Cancer Study
Cancer Epidemiology, Biomarkers & Prevention, April 4, 2013
Li T et al. - Hemoglobin adducts of 4-ABP and 2,6-DMA were significantly and independently associated with increased bladder cancer risk among lifelong nonsmokers in Shanghai, China. Methods The Shanghai bladder Cancer Study enrolled 581 incident bladder cancer cases and 604 population controls. Each participant was solicited for his/her history of tobacco use and other lifestyle factors, and donation of blood and urine specimens. Red blood cell lysates were used to quantify ...
Depression, anxiety and the bladder
LUTS: Lower Urinary Tract Symptoms, April 3, 2013
Sakakibara R et al. - Authors aimed to delineate bladder dysfunction in patients with depression/anxiety by reviewing the literature. Although the frequency of LUTS among the depression cohort is not elevated, depression/anxiety is obviously a risk factor for OAB. This finding presumably reflects that the bladder is under emotional control. Amelioration of bladder dysfunction is an important target in treating patients with depression/anxiety. In both the depression cohort and ...
Intravesical bacille Calmette-Guerin (BCG) in immunologically compromised patients with bladder cancer
BJU International, February 5, 2013
Herr HW et al. - To investigate the outcomes of bacille Calmette-Guerin (BCG) therapy in patients with bladder cancer who were immunologically compromised. The authors conclude that intravesical BCG is safe and effective in immunologically compromised patients with bladder cancer. Transplant patients fare worse and should be considered for early cystectomy if they fail BCG therapy.
In all, 45 immunosuppressed patients with high-grade non-muscle-invasive bladder ...
Chromosomal instability and bladder cancer: the UroVysionTM test in the UroScreen study
BJU International, February 5, 2013
Bonberg N et al. - To explore changes at chromosomes 3, 7, 17 and 9p21 in order to assess associations with bladder cancer for possible improvements of the UroVysion assay regarding screening. The UroVysion assay showed a reasonable performance in detecting bladder cancer in the present study population and shared positive test results with cytology, which is much cheaper. A simpler, faster and cheaper version of the UroVysion assay might rely on the very strong correlations between ...
Urge perception index of bladder hypersensitivity
The Journal of Urology, May 6, 2013
Fujihara A et al. - Authors evaluated the impact of the urge perception index on the definition of overactive bladder severity. The urge perception index, an integrated parameter of patient reported bladder perception and voided volume, could be promising to quantify the severity of overactive bladder or bladder hypersensitivity by bladder diary analysis.