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Fell AKM et al. – A significantly higher percentage of neutrophils was observed in cement production workers during the exposed period compared with the non–exposed period and with the external reference group. This elevated percentage corresponded with an elevated IL–1beta concentration. These data indicate that cement aerosol exposure in concentrations below the Norwegian occupational limits (respirable dust, 5 mg/m3; total dust, 10 mg/m3) may cause airway inflammation.


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Anne Kristin Moller Fell, 11/10/09

It is not clear whether the increased percentage of neutrophils as observed in our study represents an early stage of respiratory disease or if it is only a marker of exposure without clinical consequences. Nevertheless, spirometric surveillance should be carried out at regular intervals until results from follow-up studies are completed and interpreted in relation to these questions.

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