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Kurahashi K et al. – A higher respiratory frequency and a larger percentage of inspiratory time resulted in an increase in the intrinsic PEEP at the central airway, as well as a wide difference in the intrinsic PEEP between airway units. These phenomena were confirmed by a 2–compartment test–lung study. The authors demonstrated and verified an uneven distribution of intrinsic PEEP in 2 different experiments, which raised a warning that some respiratory units might have much higher intrinsic PEEP than the intrinsic PEEP measured clinically.

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