Pulmonology Medical News about telomerase gene amplification

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Correlation between morphology and human telomerase gene amplification in bronchial brushing cells for the diagnosis of lung cancer
Diagnostic Cytopathology, 11/04/09

Fan Y–B et al. – FISH can be performed on bronchial brushing specimens to detect amplification of TERC. This test may be an adjunct to cytology screening, especially in squamous–cell carcinoma, and may provide an indication of the potential of individual lesions to progress.

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Assessing HER2 gene amplification as a potential target for therapy in invasive urothelial bladder cancer with a standardized methodology: Results in 1005 patients
Annals of Oncology, 11/10/09 Relevance Score: 67%

PPFIA1 and CCND1 are frequently coamplified in breast cancer
Genes, Chromosomes and Cancer, 10/02/09 Relevance Score: 67%

Overexpression of cell division cycle 7 homolog is associated with gene amplification frequency in breast cancer
Human Pathology, 11/12/09 Relevance Score: 66%

Upregulated p27kip1 can Downregulate Survivin Expression and Inhibit Telomerase Activity in Gastric Carcinoma Cells
Cancer Investigation, 10/26/09 Relevance Score: 66%

PAX5 activates the transcription of the human telomerase reverse transcriptase gene in B cells
The Journal of Pathology, 10/08/09 Relevance Score: 66%