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Skin thickness in children treated with daily or periodical inhaled budesonide for mild persistent asthma
Pediatric Research, 10/29/09
Turpeinen M et al. – The initial 6–month budesonide treatment resulted in a greater reduction in mean skin thickness in the forearms compared with DSCG (right: –35.9 vs. –5.9 [mu]m; p=0.004; left: –30.6 vs. –7.3 [mu]m; p=0.03). At month 18, the inter–group differences were no longer significant. Budesonide inhalations in daily doses of 400 to 800 [mu]g in prepubertal children with newly detected asthma may cause minor dermal thinning. The changes were reversible during low dose or periodic treatment with budesonide.
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