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Voriconazole concentrations and outcome of invasive fungal infections
Clinical Microbiology and Infection, 10/30/09
Miyakis S et al. – The data suggest that voriconazole TDM is appropriate for all patients as soon as steady state is achieved. For non–responding patients with low trough concentrations, the association with IFI–related mortality indicates the need for dose adjustments to achieve and sustain voriconazole concentrations.
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