Pulmonology Medical News about Asthma

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Reduced FcεRI-Mediated Release of Asthma-Promoting Cytokines and Chemokines from Human Basophils during Omalizumab Therapy
International Archives of Allergy and Immunology, 10/21/09

Oliver JM et al. – Omalizumab may reduce asthma symptoms in part by suppressing the FcRI–mediated production by basophils of Th2 cytokines and selected chemokines. Anti–IgE–stimulated basophil cytokine synthesis appears more sensitive than histamine release to the loss of FcRI caused by omalizumab treatment.

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Clinical importance of identifying immunoglobulin E-mediated disease in patients with Asthma
Clinical Cornerstone, 10/01/09 Relevance Score: 96%

Bone mineral density and fractures in older men with chronic obstructive pulmonary disease or asthma
Osteoporosis International, 10/13/09 Relevance Score: 95%

The Saudi Initiative for asthma
Annals of Thoracic Medicine, 10/13/09 Relevance Score: 95%

Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study
Journal of Allergy and Clinical Immunology, 10/09/09 Relevance Score: 95%

Identification of Asthma Phenotypes using Cluster Analysis in the Severe Asthma Research Program
American Journal of Respiratory and Critical Care Medicine, 11/09/09 Relevance Score: 94%