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MMP-19 Deficiency Promotes Tenascin-C Accumulation and Allergen-induced Airway Inflammation
American Journal of Respiratory Cell and Molecular Biology, 10/26/09
Gueders MM et al. – MMP–19 is a new mediator in asthma, preventing tenascin–C accumulation and directly or indirectly controlling Th2–driven airway eosinophilia and airway hyperreactivity . This data suggest that MMP–19 might act on Th2 inflammation homeostasis through preventing tenascin protein accumulation.
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