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Expression and Significance of bag-1, bcl-2 in Non-small Cell Lung Cancer and the Correlation with Multi-drug Resistance
Chinese Journal of Lung Cancer, 10/21/09
Ma J et al. – The high expression of bag–1, bcl–2 protein and the low expression of bax protein exist in nonsmall cell lung cancer. The expression level of bag–1 protein is closely related to the differentiation degree of non–small cell lung cancer. A highly positive correlation exists between bag–1 and bcl–2 expression, and a highly negative correlation is observed between bcl–2 and bax expression. The study doesn’t provide the evidence that there is a close correlation between the expression levels of bag–1, bcl–2, bax and the multi–drug resistance in non–small cell lung cancer.
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