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See Latest ArticlesProstanoids and the Cough Reflex
Lung, 10/28/09
Maher SA et al. – Prostanoids are commonly associated with many diseases as a proinflammatory mediator; however, in the lung, prostanoids, particularly PGE2, seem to have a protective role. Inhaled PGE2 has been shown to be anti–inflammatory and a bronchodilator but causes cough. This has hindered the development of prostanoids for the treatment of airway inflammatory diseases. The authors discuss here the extensive research into the role of prostanoids in the airways and their modulation of the cough reflex.
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