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HDM induces direct airway inflammation in vivo: implications for future disease therapy
European Respiratory Journal , 10/29/09
Alba JD et al. – HDM allergen evokes non–allergic airways inflammation with an inflammatory profile similar to that of the asthmatic airway. This response, independent of the protease activity of the HDM extract, appeared to be linked to prior administration of the adjuvant AlumTM and the subsequent increase in total IgE. This finding could have important implications in the development of future asthma therapies.
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