Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. EGFR inhibitors as first-line therapy in advanced non-small cell lung cancer
Your Article Summary
See Latest ArticlesPhysiologic Cold Shock Increases Adherence of Moraxella catarrhalis to and Secretion of Interleukin 8 in Human Upper Respiratory Tract Epithelial Cells
The Journal of Infectious Diseases, 10/29/09
Spaniol V et al. – The authors show that a 26°C cold shock up-regulates the expression of UspA1, a major adhesin and putative virulence factor of M. catarrhalis, by prolonging messenger RNA half–life. Cold shock promotes M. catarrhalis adherence to upper respiratory tract cells via enhanced binding to fibronectin, an extracellular matrix component that mediates bacterial attachment. Exposure of M. catarrhalis to 26°C increases the outer membrane protein–mediated release of the proinflammatory cytokine interleukin 8 in pharyngeal epithelial cells.
Related Articles
The evaluation of putative endogenous control housekeeping genes for real-time polymerase chain reaction expression studies in Moraxella catarrhalis
Diagnostic Microbiology and Infectious Disease, 10/22/09
Relevance Score: 68%
Determinants of Moraxella catarrhalis colonization in healthy Dutch children during the first 14 months of life
Clinical Microbiology and Infection, 11/11/09
Relevance Score: 67%
Acute Otitis Media Caused by Moraxella catarrhalis: Epidemiologic and Clinical Characteristics
Clinical Infectious Diseases, 11/10/09
Relevance Score: 65%
Today in Pulm/Thoracic Infections...keeping you current
Receive free subspecialty "5-minute updates" via email
Chronic Obstructive Pulmonary Disease: Role of Bacteria and Updated Guide to Antibacterial Selection in the Older Patient
Drugs & Aging, 11/25/09
Laboratory Surge Response to Pandemic (H1N1) 2009 Outbreak, New York City Metropolitan Area, USA
Emerging Infectious Diseases, 11/25/09
Duration of antibiotic therapy in hospitalized patients with community-acquired pneumonia
European Respiratory Journal , 11/25/09
Sponsor
Article Search
Sponsor