Pulmonology

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Topics in Pulmonology

Apnea/Sleep Disorders

Basic Science/Genetics

CV/Thromboembolic

Clinical Pharmacology

Cystic Fibrosis

Diagnostic/Lung Function

Economics of Medicine

Lung/Thoracic Oncology

Occupational Health

Pediatric Pulmonology

Pulm/Thoracic Infections

Restrictive Lung Dz

Transplantation

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A Longer Duration of Polymyxin B-Immobilized Fiber Column Hemoperfusion Improves Pulmonary Oxygenation in Patients With Septic Shock
Shock, 10/20/09

Mitaka C et al. – Endotoxin plays an important role in the pathogenesis of septic shock. Exposure of endothelial cells to endotoxin activates endothelial cells and increases the surface expression of adhesion molecules, markers of endothelial damage in organ dysfunction. A longer duration of PMX treatment may improve the pulmonary oxygenation associated with decreased adhesion molecules in septic shock.

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