Pulmonology Medical News about Pituitary-Adrenal Axis Activation

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Hypothalamic-Pituitary-Adrenal Axis Activation in Obstructive Sleep Apnea: The Effect of Continuous Positive Airway Pressure Therapy
Journal of Clinical Endocrinology and Metabolism, 10/15/09

Henley DE et al. – Obstructive sleep apnea (OSA) is a common condition with significant cardiovascular and metabolic comorbidity. Untreated compared to treated OSA is associated with marked disturbances in ACTH and cortisol secretory dynamics, resulting in prolonged tissue exposure to disordered, elevated hormone levels.

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11beta-Hydroxysteroid Dehydrogenase Type 1 and Its Role in the Hypothalamus-Pituitary-Adrenal Axis, Metabolic Syndrome, and Inflammation
Journal of Clinical Endocrinology and Metabolism, 10/21/09 Relevance Score: 66%

Stress Induced Hypothalamus-Pituitary-Adrenal Axis Responses and Disturbances in Psychological Profiles in Men With Chronic Prostatitis/Chronic Pelvic Pain Syndrome
The Journal of Urology, 10/14/09 Relevance Score: 66%

The pituitary-adrenal axis in adult thalassaemic patients
European Journal of Endocrinology, 11/02/09 Relevance Score: 65%

Growth inhibition of thyroid follicular cell-derived cancers by the opioid growth factor (OGF) - opioid growth factor receptor (OGFr) axis
BMC Cancer, 10/21/09 Relevance Score: 65%

Selective FLT3 inhibitor FI-700 neutralizes Mcl-1 and enhances p53-mediated apoptosis in AML cells with activating mutations of FLT3 through Mcl-1/Noxa axis
Leukemia, 10/21/09 Relevance Score: 65%