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Sood A et al. – Systemic oxidant stress, primarily assessed by plasma F2–isoprostanes, was not independently associated with asthma and therefore may not explain the obesity–asthma association in women. The asthma–oxidant stress association is confounded by sex and obesity. This study is limited by the inability to measure airway oxidant stress. It is possible that another (as yet undetermined) measure of systemic oxidant stress may be more relevant in asthma.

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