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Survival after trimodality therapy for malignant pleural mesothelioma: Radical Pleurectomy, chemotherapy with Cisplatin/Permetrexed and radiotherapy
Lung Cancer, 10/09/09
Bolukbas S et al. – The trimodality therapy concept with RP demonstrates promising results in terms of long–term survival, morbidity and mortality. The authors propose that a surgical philosophy of limiting the procedure related morbidity while achieving comparable cytoreductive results allows patients to maintain physiological reserve to be eligible for multimodality treatment options in the long–term. The observed and theoretical benefits of this trimodality treatment approach warrant confirmation in larger RCT.
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