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See Latest ArticlesDiabetes Mellitus and Bone Disease in Cystic Fibrosis
Seminars in Respiratory and Critical Care Medicine, 09/24/09
Curran DR et al. – Therapy for cystic fibrosis–related diabetes differs substantially from type 2 DM, with careful attention to prandial glycemic excursions crucial to controlling its metabolic effects. Bone disease, including osteopenia and osteoporosis, also occurs with increased frequency in cystic fibrosis, owing to defects in intestinal absorption, chronic inflammation, lung disease, low body weight, and gonadal dysfunction. The pathogenesis, implications, diagnosis, and therapy of cystic fibrosis–related bone demineralization are discussed, with attention to recommended approaches to prevention of and treatment of established bone disease.
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