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Sandrini A et al. – This review summarizes the clinical use of FeNO in asthma. It covers the relationship between FeNO and the underlying eosinophilic inflammation, the pathophysiology and production of FeNO, technical aspects of FeNO measurement and potential confounding factors in interpreting levels. FeNO reference values and the role of FeNO in asthma assessment, diagnosis and management are also discussed.

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