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Airway obstruction is increased in Pneumocystis-colonized HIV-infected outpatients
Journal of Clinical Microbiology, 09/17/09
Morris A et al. – The authors investigated the relationship of Pneumocystis colonization, sputum matrix metalloprotease levels, and airway obstruction in a cohort of HIV–infected outpatients. Pneumocystis–colonized subjects had worse airway obstruction and higher sputum matrix metalloprotease–12 levels, suggesting that Pneumocystis colonization may be important in HIV–associated chronic obstructive pulmonary disease.
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