Pulmonology Medical News about chronic obstructive pulmonary disease; pulmonary hypertension

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Update on pulmonary hypertension complicating chronic obstructive pulmonary disease
International Journal of COPD, 09/09/09

Jyothula S et al. – The major cause of PH in COPD is hypoxemia leading to vascular remodeling. Echocardiogram is the initial screening tool of choice for PH. This simple noninvasive test can provide an estimate of right ventricular systolic and right atrial pressures. Right heart catheterization remains the gold standard to diagnose PH. It provides accurate measurement of mean PAP and pulmonary capillary wedge pressure. Oxygen therapy remains the cornerstone therapeutic for hypoxemia in COPD patients. Anecdotal reports suggest utility of PDE5–inhibitors and prostacyclin to treat COPD–related PH.

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