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Plasmacytoid dendritic cells during infancy are inversely associated with childhood respiratory tract infections and wheezing
Journal of Allergy and Clinical Immunology, 09/08/09
Upham JW et al. – In children with a family history of atopy, relative deficiency of circulating pDCs during infancy appears to be a risk factor for more frequent and more severe respiratory tract infections, wheezing, and a diagnosis of asthma. Infants with higher numbers of pDCs are protected against these outcomes.
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