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See Latest ArticlesLung cancer susceptibility and genetic polymorphism of DNA repair gene XRCC4 in Taiwan
Cancer Biomarkers, 09/10/09
Hsu N–Y et al. – Non–homologous end–joining (NHEJ) system is a major route in repairing double strand breaks (DSBs), and is important in maintaining the genome stability. The gene XRCC4 is a central role of the NHEJ system, and it is critical in carcinogenesis. The G allele of the XRCC4 G–1394T may be responsible for lung carcinogenesis and maybe useful in early detection and prevention of lung cancer.
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