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See Latest ArticlesPeroxisome proliferator activated receptor-gamma (PPAR-gamma) ligands induce heme oxygenase-1 in lung fibroblasts by a PPAR-gamma-independent, glutathione-dependent mechanism
Lung Cellular and Molecular Physiology, 09/11/09
Ferguson HE et al. – These results suggest that CDDO and similar electrophilic PPAR–gamma ligands may have great clinical potential as anti–fibrotic agents, not only through direct effects on fibroblast differentiation and function, but indirectly by bolstering antioxidant defenses.
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