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Coagulation factors in the airways in moderate and severe asthma and the effect of inhaled steroids
Thorax, 09/15/09

Brims FJH et al. – Untreated moderate asthma is associated with increased fibrinolysis that is corrected by ICS. Severe asthma and high dose corticosteroid therapy is associated with a pro–fibrinogenic, anti–fibrinolytic environment in the airways. This study suggests that inhibition of fibrin deposition in severe asthma may be a therapeutic approach.

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Clinical importance of identifying immunoglobulin E-mediated disease in patients with Asthma
Clinical Cornerstone, 10/01/09 Relevance Score: 96%

Bone mineral density and fractures in older men with chronic obstructive pulmonary disease or asthma
Osteoporosis International, 10/13/09 Relevance Score: 95%

The Saudi Initiative for asthma
Annals of Thoracic Medicine, 10/13/09 Relevance Score: 95%

Consistently very poorly controlled asthma, as defined by the impairment domain of the Expert Panel Report 3 guidelines, increases risk for future severe asthma exacerbations in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study
Journal of Allergy and Clinical Immunology, 10/09/09 Relevance Score: 95%

Identification of Asthma Phenotypes using Cluster Analysis in the Severe Asthma Research Program
American Journal of Respiratory and Critical Care Medicine, 11/09/09 Relevance Score: 94%