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Alveolar Macrophage Dysregulation in Hermansky-Pudlak Syndrome Type-1
American Journal of Respiratory and Critical Care Medicine, 09/10/09
Rouhani FN et al. – In HPS–1, alveolar inflammation predominantly involves macrophages and is associated with high lung concentrations of cytokines and chemokines. HPS–1 alveolar macrophages provide a model system in which to study the pathogenesis and treatment of HPS pulmonary fibrosis.
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