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Bruinstroop E et al. – It is safe to use D–dimer testing in combination with a clinical decision rule in patients of all ages, patients presenting with a suspected recurrent venous thromboembolism or inpatients with suspected pulmonary embolism. As patients with recurrent venous thromboembolism, elderly patients and inpatients have higher levels of D–dimer, D–dimer testing has a low specificity and the need for additional radiological testing is increased.

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