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Evolution of the Capsular Regulatory Genes in Streptococcus pneumoniae
The Journal of Infectious Diseases, 08/27/09
Varvio SL et al. – The survey of epidemiological data showed a tendency of the ancestral type of the capsular regulatory genome to be associated with carriage and the laterally transferred sequences to be associated with invasive disease isolates. The regulatory gene region shows mosaic structures that have signatures of recent recombination events, reminiscent of structures known from antibiotic resistance genes.
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