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See Latest ArticlesA phase I/II study of gti-2040 plus docetaxel as second-line treatment in advanced non-small cell lung cancer: a study of the PMH Phase II Consortium
Journal of Thoracic Oncology, 09/01/09
Leighl NB et al. – The combination of GTI-2040 (an antisense oligonucleotide) + docetaxel is not superior to docetaxel alone in previously treated NSCLC.
Methods- 29 patients with advanced solid tumors, PS 0-2, no symptomatic CNS metastases, adequate organ and BM function, and ≥ 1 prior chemotherapy regimen were treated with escalating doses of GTI-2040 + docetaxel
- GTI-2040 + docetaxel was not superior to docetaxel alone in the treatment of previously treated NSCLC
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