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Initiation of Inappropriate Antimicrobial Therapy Results in a 5-Fold Reduction of Survival in Human Septic Shock
Chest, 08/26/09
Kumar A et al. – Inappropriate initial antimicrobial therapy for septic shock occurs in about 20% of patients and is associated with a fivefold reduction in survival. Efforts to increase the frequency of appropriateness of initial antimicrobial therapy must be central to efforts to reduce the mortality of septic shock.
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