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Targeting and Imaging Signature Caveolar Molecules in Lungs
Proceedings of the American Thoracic Society, 08/25/09
Massey KA et al. – Targeting imaging agents to a single organ could facilitate the high–resolution, in vivo imaging of molecular events. In addition, genetic and acquired diseases primary to a single organ, such as cystic fibrosis, tuberculosis, lung cancer, pulmonary fibrosis, pulmonary hypertension, and acute respiratory distress syndrome, could be specifically targeted in the lung. By targeting and concentrating imaging agents or therapeutics to the lungs, deleterious side effects can be avoided with greater efficacy at much lower dosages.
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