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Sleep-Related Respiratory Abnormalities and Arousal Pattern in Achondroplasia during Early Infancy
The Journal of Pediatrics, 08/26/09
Ednick M et al. – Infants with achondroplasia have significant SDB during early infancy. SDB in infants with achondroplasia is not associated with alteration in sleep architecture, possibly because of attenuation of the arousal response. The authors speculate that the concomitant increased apneic events and decreased arousal response will lead to vulnerability in these infants and may underlie the pathophysiologic mechanism of sudden unexpected death in this population.
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