Pulmonology Medical News about N-acetylcysteine

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N-acetylcysteine Inhibits Alveolar Epithelial-Mesenchymal Transition
Lung Cellular and Molecular Physiology, 08/06/09

Felton VM et al. – NAC prevents EMT in AEC in vitro, at least in part through replenishment of intracellular GSH stores and limitation of TGF–beta–1–induced intracellular ROS generation. The authors speculate that beneficial effects of NAC on pulmonary function in IPF may be mediated by inhibitory effects on alveolar EMT.

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The effects of N-acetylcysteine on testicular damage in experimental testicular ischemia/reperfusion injury
Pediatric Surgery International, 11/18/09 Relevance Score: 80%

Antiemetic use in acetaminophen poisoning: How does the route of N-acetylcysteine administration affect utilization
Journal of Medical Toxicology, 11/06/09 Relevance Score: 80%