Your Messages Inbox
Most Viewed Abstracts
1. Report Shows Shift in Starting Salaries for Physicians 2. 2008 Exclusive Survey—Earnings: Good news for primary care income 3. Medicare pay-for-reporting effort draws fire from frustrated doctors 4. Debunking Myths in the US Healthcare System 5. EGFR inhibitors as first-line therapy in advanced non-small cell lung cancer
Your Article Summary
See Latest ArticlesThrombin Induces Fibronectin-Specific Migration of Pulmonary Microvascular Endothelial Cells: Requirement of Calcium-Calmodulin Dependent Protein Kinase II
Lung Cellular and Molecular Physiology, 08/06/09
Meoli DF et al. – The findings illustrate EC heterogeneity in a single tissue and indicate a novel role for CaMKII in mediating EC migration. Because PMVEC have been shown to have impressive proliferative potential, thrombin/fibronectin stimulated migration of these cells to a site of injured endothelium is a potential mechanism by which thrombin contributes to the development of vascular lesions in PAH.
R James White, 08/06/09
| It's well known that fibronectin is rich in vessels that are injured with pulmonary hypertension. Our data support an important role for thrombin in directing cells to areas of vascular injury where they could abnormally proliferate and contribute to disease progression. We think this data supports early clinical trials of anti-thrombin drugs in pulmonary hypertension patients. |
Today in Basic Science/Genetics...keeping you current
Receive free subspecialty "5-minute updates" via email
Respiratory Viral RNA on Toys in Pediatric Office Waiting Rooms
The Pediatric Infectious Disease Journal, 11/16/09
Absence of inflammation and pneumonia during infection with non-pigmented Yersinia pestis reveals new role for the pgm locus in pathogenesis
Infection and Immunity, 10/30/09
Pattern of Antioxidant and DNA Repair Gene Expression in Normal Airway Epithelium Associated with Lung Cancer Diagnosis
Cancer Research, 11/17/09
Today in CV/Thromboembolic...keeping you current
Receive free subspecialty "5-minute updates" via email
Hemodynamic and Gas Exchange Effects of Sildenafil in Patients with COPD and Pulmonary Hypertension
American Journal of Respiratory and Critical Care Medicine, 10/30/09
The Use of Sildenafil in Persistent Pulmonary Hypertension of the Newborn
American Journal of Perinatology, 10/28/09
Vena cava filter occlusion and venous thromboembolism risk in persistently anticoagulated patients: A prospective, observational cohort study
Chest, 11/03/09
Sponsor
Article Search
Sponsor