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Potential role of matrix metalloproteinase-2,-9 and tissue inhibitors of metalloproteinase-1,-2 in exudative pleural effusions
Clinical and Investigative Medicine, 08/06/09
Vatansever S et al. – Determination of TIMP–2 in pleural fluid may contribute to differentiate TP from MP. These results suggest that overproduction of MMP–9 and TIMP–2 is associated with accumulation of the pleural effusion in malignancy. Further studies with a greater number of patients are needed to confirm this hypothesis.
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