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Obliterative bronchiolitis following lung transplantation: from old to new concepts
Transplant International, 07/31/09
Verleden GM et al. – Lung transplantation has come of age and is now considered a valid treatment for selected patients with end–stage lung disease. In recent years, survival rates have much improved, although the development of chronic rejection, characterized by a progressive and irreversible decline in FEV1, which is clinically defined as bronchiolitis obliterans syndrome remains the major obstacle to long–term survival.
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