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See Latest ArticlesPulmonary alveolar microlithiasis: review and management
Current Opinion in Pulmonary Medicine, 08/06/09
Tachibana T et al. – The gene responsible for PAM, SLC34A2, has been identified. It encodes a type IIb sodium–dependent phosphate transporter, the function of which provides an insight into the pathogenesis of this disease. The demonstration of a mutation in the SLC34A2 gene helps to confirm the diagnosis of PAM. Characteristic chest CT findings that include irregular thickening of perilobular interstitium and calcification along perilobular structures correlate with specific pathological findings. Serum levels of surfactant proteins A and D correlate with the progression of the disease, and may be a useful monitoring tool.
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Today in Diagnostic/Lung Function...keeping you current
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