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See Latest ArticlesCharacterization and peripheral blood biomarker assessment of anti-Jo-1 antibody-positive interstitial lung disease
Arthritis & Rheumatism, 07/13/09
Richards TJ et al. - In this large cohort of anti-Jo-1 antibody-positive individuals, the incidence of ILD approached 90%. Multiplex ELISA demonstrated disease-specific associations between anti-Jo-1 antibody-positive ILD and serum levels of CRP as well as the interferon-gamma-inducible chemokines CXCL9 and CXCL10, highlighting the potential of this approach to define biologically active molecules contributing to the pathogenesis of myositis-associated ILD.
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