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Impact of frequency of COPD exacerbations on pulmonary function, health status and clinical outcomes
International Journal of COPD, 06/25/09
Anzueto A et al. - In the placebo-treated patients increased frequency of exacerbations was associated with larger decrements in FEV1, TDI, and SGRQ. A reduction in the frequency of exacerbations is associated with changes that are considered meaningful in these clinical outcomes.
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