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Genetic Polymorphisms of the Serotonin Transporter, but Not the 2a Receptor or Nitric Oxide Synthetase, Are Associated with Pulmonary Hypertension in Chronic Obstructive Pulmonary Disease
Respiration, 06/24/09
Ulrich S et al. - In this COPD cohort the authors confirm that PH is frequent and usually mild, but out of proportion in a subgroup. The authors found a significant association of the L-allelic variant of 5HTT with PH overall and especially in out-of-proportion PH. These findings may point towards a role of the serotonin system in COPD-PH and warrant further studies.
Today in Basic Science/Genetics...keeping you current
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Polymorphisms in the CASPASE Genes and Survival in Patients With Early-Stage Non-Small-Cell Lung Cancer
Journal of Clinical Oncology, 10/16/09
Absence of inflammation and pneumonia during infection with non-pigmented Yersinia pestis reveals new role for the pgm locus in pathogenesis
Infection and Immunity, 10/30/09
Association and interaction analyses of eight genes under asthma linkage peaks
Allergy, 10/15/09
Today in COPD...keeping you current
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Effect of Fluticasone With and Without Salmeterol on Pulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Annals of Internal Medicine, 10/20/09
Bone mineral density and fractures in older men with chronic obstructive pulmonary disease or asthma
Osteoporosis International, 10/13/09
Today in CV/Thromboembolic...keeping you current
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Is pulmonary arterial hypertension really a late complication of systemic sclerosis
Chest, 10/09/09
The Use of Sildenafil in Persistent Pulmonary Hypertension of the Newborn
American Journal of Perinatology, 10/28/09
Continuous Positive Airway Pressure vs. Pressure Support Ventilation in Acute Cardiogenic Pulmonary Edema: A Randomized Trial
The Journal of Emergency Medicine, 10/13/09
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