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Amino acid changes in elongation factor-Tu of Mycoplasma pneumoniae and Mycoplasma genitalium influence fibronectin binding
Infection and Immunity, 06/23/09
Balasubramanian S et al. - Synthetic peptides corresponding to this region of MPN EF-Tu block both recombinant MPN EF-Tu and radiolabeled M. pneumoniae cell binding to Fn. MG EF-Tu 340-358 peptides exhibit minimal blocking activity, reinforcing the specificity of EF-Tu-Fn interactions as mediators of microbial colonization and tissue tropism.
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